Species Profile - Cylindrospermopsis raciborskii

Cylindrospermopsis raciborskii

Common Name: Cylindro

Synonyms and Other Names:

Anabaena raciborskii

Rex Lowe

Identification: This species of cyanobacterium (blue-green alga) is composed of trichomes (chained filaments) that are solitary and straight. In Mona Lake, within the Lake Michigan basin, their tube-shaped cells contain groups of scattered gas vesicles and are divided by barely visible walls (Hong et al. 2006). In other populations, such as in Lake Constance near Ottawa, Ontario, the cell walls are thick and conspicuous (Hamilton et al. 2005). The terminal cells may differentiate into cone-shaped heterocytes. Akinetes (thick-walled spore-like structures) are cylindrical to oval-shaped, found singly or in pairs, near the terminal heterocytes (Hong et al. 2006). Both straight and coiled trichomes of this species exist in different locations around the world. Morphological variation in trichomes, vegetative cells and heterocytes can occur even among very similar genetic isolates of C. raciborskii, depending on abiotic conditions (Saker et al. 1999a, Saker and Neilan 2001, Shafik et al. 2003).

Size: In Mona Lake, trichomes range from 51–311 µm in length and 1.7–4.2 µm in width, heterocytes are 5–11 µm by 2–5 µm, and akinetes are 8–16 µm by 2–5 µm (Hong et al. 2006).

Native Range: The genus Cylindrospermopsis is regarded as tropical/subtropical in origin, but it has expanded into temperate areas, particularly the northern hemisphere. The strain of C. raciborskii introduced to the Great Lakes may have originated in South America.


This map only depicts Great Lakes introductions. Click here for Great Lakes region collection information

Great Lakes Nonindigenous Occurrences: Cylindrospermopsis raciborskii was recorded from Mona Lake in 2002 and 2003 as well as Muskegon Lake in 2005, both of which are in the Lake Michigan basin, Michigan (Hong et al. 2006). There is a single earlier record of this species in Lake Erie from 1971 (Taft and Taft 1971) that may have been previously misidentified as Anabaenopsis raciborskii (Kling 2004). This species was also more recently recorded from Lake Erie (Conroy et al. 2006).

Table 1. Great Lakes region nonindigenous occurrences, the earliest and latest observations in each state/province, and the tally and names of HUCs with observations†. Names and dates are hyperlinked to their relevant specimen records. The list of references for all nonindigenous occurrences of Cylindrospermopsis raciborskii are found here.

State/Province	Year of earliest observation	Year of last observation	Total HUCs with observations†	HUCs with observations†
Michigan	2002	2005	2	Muskegon; Pere Marquette-White
Ohio	1971	1971	1	Lake Erie

Table last updated 9/30/2019

† Populations may not be currently present.

Ecology: Akinetes may persist as spores in the sediments for long periods of time. Akinete formation may be triggered by cold temperatures or large temperature fluctuations, and requires high levels of reactive phosphorus (Moore et al. 2003, Moore et al. 2005). In temperate regions, germination occurs roughly in response to water temperature rising to 22–24°C (Hong et al. 2006, Padisak 2003). Akinetes are probably necessary to stimulate a new season’s growth, providing the initial bloom with concentrated phosphorus. Upon germination, akinetes elongate, split open, and the germling cells that emerge eventually become trichomes (Moore et al. 2004). In tropical or subtropical waters, this species is perennial and akinetes rarely develop (Padisak 2003).

Algae blooms consist of trichomes found in and below the euphotic zone, not at the surface (Saker and Griffiths 2001). Concentrations of this species in Mona and Muskegon Lakes have remained low during late summer sampling, accounting for 6% of phytoplankton count in 2002 and 2003 in the former and < 1% in 2005 in the latter, possibly due to temperature limitations (Hong et al. 2006). This species can reach very high concentrations (e.g., 176 000 units ml-1 in Newnans Lake, Florida) (Chapman and Schelske 1997).

In Constance Lake, Ontario, C. raciborskii blooms appear to be controlled by water temperature and not nutrients (Hamilton et al. 2005). This species is capable of fixing atmospheric nitrogen in its heterocytes in response to low cell nitrogen concentration, as well as taking up phosphorus at low concentrations (Shafik et al. 2001, Sprober et al. 2003). The relatively high phosphorus uptake affinity and storage capacity confer a competitive advantage upon this species both in deep lakes with nutrient stratification as well as in lakes lacking such nutrient gradation (Istvanovics et al. 2000). Moreover, this species may also compete well for light in destratified lakes (Antenucci et al. 2005) and artificially mixed reservoirs (Burford et al. 2006). Conditions that are often associated with blooms of C. raciborskii include: low flow; low water level; low nitrogen to phosphorus ratio; high water temperature; stable thermal stratification; increased retention time; high pH; high sulfate concentration; anoxia in at least some strata; high turbidity; high incident irradiation; and low macrophyte biomass (Berger et al. 2006, Bormans et al. 2004, Bouvy et al. 1999, Bouvy et al. 2006, Bowling 1994, Briand et al. 2002, Chellappa and Costa 2003, Da Silva et al. 2001, Fabbro and Duivenvoorden 1996, Hong et al. 2006, Mayer et al. 1997, McGregor and Fabbro 2000, Ramberg 1987, Saker and Neilan 2001, Tucci and Sant’Anna 2003). The optimum temperature for growth is 25–30°C, although growth can occur between 15°C and 35°C, depending on the strain. The optimum light intensity for growth is 80–121 µmol m^-2 s^-1, but growth occurs at levels as low as 22 µmol m^-2 s^-1 (Briand et al. 2004, Chonudomkul et al. 2004, Saker and Griffiths 2000, Shafik et al. 2001). The maximum salinity tolerance is 4 g L^-1 NaCl (Moisander et al. 2002).

Some strains of this species are capable of producing cylindrospermopsin, a toxic compound that affects the human liver and kidneys, as well as anatoxin-a and saxitoxin, which both act as paralytic shellfish neurotoxins (Schembri et al. 2001). Increased production of cylindrospermopsin is associated with long periods of growth in high light intensity conditions (Dyble et al. 2006), in the presence of a fixed nitrogen source (Saker and Neilan 2001), and at lower water temperatures (Saker and Griffiths 2000).

Means of Introduction: Potential modes of introduction of this species to the Lake Michigan watershed include shipping, recreational boating, waterfowl, and/or wind dispersal (Hong et al. 2006).

Status: Established.

Great Lakes Impacts:

There is little or no evidence to support that Cylindrospermopsis raciborskii has significant environmental impacts in the Great Lakes.

Realized:
Cylindrospermopsis raciborskii is found in relatively low abundances in Lake Erie (16-1,942 trichomes/mL), Muskegon Lake (~42 trichomes/mL), and Bear Lake (~1,000 trichomes/mL) (Conroy et al. 2007, Xie et al. 2011). As a result of these low abundances, many of the negative environmental impacts seen in other locations around the world where there are higher densities are not yet occurring in the Great Lakes basin.

Potential:
Some strains of C. raciborskii produce a variety of toxins including cylindrospermopsin, anatoxin-a, and saxitoxin. These toxins have been responsible for fish kills in a reservoir in Brazil and cattle deaths in Australia (De Souza et al. 1998, Saker et al. 1999b, Thomas et al. 1998). Cylindrospermopsin has been found to bioaccumulate in certain species of mollusks, crayfish, and snails; in some cases this exposure was toxic (Kiss et al. 2002, Saker et al. 2004, Saker and Eagleshame 1999, White et al. 2006, Metcalf et al. 2002). Anatoxin produced by some strains of C. raciborskii has been found to affect snails (Kiss et al. 2002).

At high densities (e.g., > 90% phytoplankton biomass) in more tropical climates, C. raciborskii can cause a reduction in biodiversity. This is because of its ability to fix atmospheric nitrogen, sequester phosphorous, and move throughout the water column (Borics et al. 2000, Bouvy et al. 2001, Dobberfuhl 2003, Leonarda and Paerl 2005). In the St. Johns River System, Florida, C. raciborskii appears to reduce the size and diversity of zooplankton by sequestering nutrients and making them unavailable to grazers in the water column (Leonard and Paerl 2005). Some rotifers and cladocerans exhibit reduced feeding rates, growth rates, or growth potential in the presence of C. raciborskii (Hawkins and Lampert 1989, Nogueira et al. 2004, Rothaupt 1991). C. raciborskii may also cause phytoplankton diversity to decrease, as has been observed in Lake Jesup, Florida (Dobberfuhl 2003) and a pond in Hungary (Borics et al. 2000).

Cylindrospermopsis raciborskii has a moderate socio-economic impact in the Great Lakes.
Realized:
Cylindrospermopsis raciborskii is found in relatively low abundances throughout the Great Lakes and as a result these populations do not yet exhibit the negative socio-economic impacts seen in other locations around the world with larger populations of C. raciborskii.

Potential:
A history of human health and water quality impacts elsewhere in the world under conditions similar to those found in the Great Lakes warrants significant concern, resulting in the assessment of this species as likely to have moderate socioeconomic impact.

Cylindrospermopsin from toxic C. raciborskii strains has caused liver damage and even death in humans, when the species occurs in water supply systems (Bernard et al. 2003; Falconer and Humpage 2006; Hawkins et al. 1985). Cylindrospermopsin also has the potential to be genotoxic or carcinogenic in humans and to cause acute skin reactions in people on contact (Falconer and Humpage 2001; Falconer and Humpage 2006; Humpage et al. 2000; Shen et al. 2002; Stewart et al. 2006).

Strains of C. raciborskii that produce toxins can severely impact water quality both in drinking water for humans and as a result of bioaccumulation in aquatic organisms (Bernard et al. 2003, Bouke et al. 1983, Hawkins et al. 1985, Kiss et al. 2002, Saker et al. 2004, Saker and Eagleshame 1999, White et al. 2006).

Cylindrospermopsin is a potent inhibitor of protein synthesis, an irritant, and causes cutaneous sensitizing that could be harmful to recreational users of impacted water bodies; to date, however, populations in the Great Lakes basin have not been known to produce cylindrospermopsin (Conroy et al. 2007, Stewart et al. 2006, Xie et al. 2011). Treatment of a C. raciborskii bloom with copper sulfate resulted in contamination of a reservoir on Palm Island, Australia with cylindrospermopsin. After drinking the contaminated water, 141 people were hospitalized with hepatoenteritis and other symptoms affecting kidneys, adrenal glands, small intestine, lungs, thymus, and heart (Bernard et al. 2003, Bouke et al. 1983, Hawkins et al. 1985). There is also accumulating evidence that cylindrospermopsin is carcinogenic (Falconer and Humpage 2001).

There are multiple reports of toxic C. raciborskii blooms occurring in aquaculture ponds in Australia and other tropic regions. This often results in bioaccumulation of cylindrospermopsin within the organisms intended for harvest and the economic loss of infected organisms. Such blooms also create a risk of the toxin getting into the human food market if not detected soon enough (Saker and Eaglesham 1999).

Furthermore, in areas outside of the Great Lakes, the overwhelming biomass of C. raciborskii blooms in association with the changes to the biodiversity of the system can negatively impact the natural value of the area (Leonard and Paerl 2005).

There is little or no evidence to support that Cylindrospermopsis raciborskii has significant beneficial effects in the Great Lakes.

Management:

Regulations (pertaining to the Great Lakes region)
There are no known regulations for this species.

Note: Check federal, state/provincial, and local regulations for the most up-to-date information.

Control
Biological
There are no known organisms that can degrade cylindrospermopsin. However, several studies have found that a variety of unidentified bacteria degraded 100% of saxitoxin, another toxin produced by C. raciborskii (Donovan et al. 2008, Ho et al. 2012).

Physical
Cylindrospermopsis raciborskii blooms are often associated with a stratified water column, which is one of the reasons they are so prevalent in shallow water bodies with a long turnover period. A mechanical system can be used to create artificial destratification to increase vertical mixing, introduce oxygen, and reduce internal nutrient loading. The installation of a destratification mechanism was attempted in a reservoir in Australia. While there was a reduction in internal nutrient loading, the increased turbidity of the water yielded a competitive advantage for C. raciborskii, which can move throughout the water column to compete for light (Atenucci et al. 2005).

Cylindrospermopsin can be absorbed by activated carbon with high mesopor capacity, and nanofiltration may be another viable option, but not enough research has been done to be conclusive about the efficacy of either technique. Saxitoxins can be absorbed by activated carbons that have a large fraction of the pores that are smaller than 1 nm (Westrick 2010).

Chemical
Cylindrospermopsin can be inactivated by chlorine, ozone, and hydroxyl radical treatments. Saxitoxin can be inactivated by chlorine (Westrick 2010). However, the use of copper-based algicides may inhibit the degradation of cylindrospermopsin (Smith et al. 2008).

Note: Check state/provincial and local regulations for the most up-to-date information regarding permits for control methods. Follow all label instructions.

Remarks: Climate change may be contributing to the expansion of this species in temperate latitudes (Briand et al. 2004, Hamilton et al. 2005). If water temperatures continue to increase and water levels continue to drop, studies suggest these isolated populations within the Great Lake could become much more prominent (Conroy et al. 2007, Wiedner et al. 2007, Xie et al. 2007).

Genetic similarities exist between strains of C. raciborskii from Australia and Europe, Africa and Australia, and North and South America (Dyble et al. 2002, Gugger et al. 2005). The relatively recent colonization of northerly latitudes in North America, including the Great Lakes, probably involves populations originally from South America (Gugger et al. 2005).

References: (click for full references)

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Berger, C., N. Ba, M. Gugger, M. Bouvy, F. Rusconi, A. Coute, M. Troussellier, and C. Bernard. 2006. Seasonal dynamics and toxicity of Cylindrospermopsis raciborskii in Lake Guiers (Senegal, West Africa). FEMS Microbiology Ecology 57(3):355-366.

Bernard, C., M. Harvey, J.F. Briand, R. Bire, S. Krys, and J.J. Fontaine. 2003. Toxicological comparison of diverse Cylindrospermopsis raciborskii strains: evidence of liver damage caused by French C. raciborskii strain. Environmental Toxicology 18(3):176-186.

Borics, G., I. Grigorszky, S. Szabo, and J. Padisak. 2000. Phytoplankton associations in a small hypertrophic fishpond in East Hungary during a change from bottom-up to top-down control. Hydrobiologia 424(1-3):79-90.

Bormans, M., P.W. Ford, L. Fabbro, and G. Hancock. 2004. Onset and persistence of cyanobacterial blooms in a large impounded tropical river, Australia. Marine and Freshwater Research 55(1):1-15.

Bouvy, M., M. Pagano, and M. Troussellier. 2001. Effects of a cyanobacterial bloom (Cylindrospermopsis raciborskii) on bacteria and zooplankton communities in Ingazeira reservoir (northeast Brazil). Aquatic Microbial Ecology 25:215-227.

Bouvy, M., N. Ba, S. Ka, S. Sane, M. Pagano, and R. Arfi. 2006. Phytoplankton community structure and species assemblage succession in a shallow tropical lake (Lake Guiers, Senegal). Aquatic Microbial Ecology 45(2):147-161.

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Briand, J.F., C. Robillot, C. Quiblier-Lloberas, J.F. Hubert, A. Coute, and C. Bernard. 2002. Environmental context of Cylindrospermopsis raciborskii (Cyanobacteria) blooms in a shallow pond in France. Water Research 36(13):3183-3192.

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Chapman, A.D., and C.L. Schelske. 1997. Recent appearance of Cylindrospermopsis (Cyanobacteria) in five hypereutrophic Florida lakes. Journal of Phycology 33:191-195.

Chellappa, N.T., and M.A.M. Costa. 2003. Dominant and co-existing species of Cyanobacteria from a eutrophied reservoir of Rio Grande do Norte State, Brazil. Acta Oecologica 24(suppl. 1):S3-S10.

Chonudomkul, D., W. Yongmanitchal, G. Theeragool, M. Kawachi, F. Kasal, K. Kaya, and M. Watanabe. 2004. Morphology, genetic diversity, temperature tolerance and toxicity of Cylindrospermopsis raciborskii (Nostocales, Cyanobacteria) strains from Thailand and Japan. FEMS Microbiology Ecology 48(3):345-355.

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Conroy, J.D., E.L. Quinlan, D.D. Kane, and D.A. Culver. 2007. Cylindrospermopsis in Lake Erie: Testing its association with other cyanobacterial genera and major limnological parameters. Journal of Great Lakes Research 33: 519-535.

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De Souza, R.C.R., M.C. Carvalho, and A.C. Truzzi. 1998. Cylindrospermopsis raciborskii (Wolosz.) Seenaya and Subba Raju (Cyanophyceae) dominance and a contribution to the knowledge of Rio Pequeno arm, Billings Reservoir, Brazil. Environmental Toxicology and Water Quality 13(1):73-81.

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Dyble, J., H.W. Paerl, and B.A. Neilan. 2002. Genetic characterization of Cylindrospermopsis raciborskii (Cyanobacteria) isolated from diverse geographic origins based on nifH and cpcBA-IGS nucleotide sequence analysis. Applied and Environmental Microbiology 68(5):2567-2571.

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Other Resources:

Great Lakes Waterlife

Author: Kipp, R.M., M. McCarthy, and A. Fusaro

Contributing Agencies:

Revision Date: 9/12/2019

Citation for this information:
Kipp, R.M., M. McCarthy, and A. Fusaro, 2019, Cylindrospermopsis raciborskii: U.S. Geological Survey, Nonindigenous Aquatic Species Database, Gainesville, FL, and NOAA Great Lakes Aquatic Nonindigenous Species Information System, Ann Arbor, MI, https://nas.er.usgs.gov/queries/greatlakes/FactSheet.aspx?SpeciesID=2651&Potential=N&Type=0, Revision Date: 9/12/2019, Access Date: 11/15/2019

This information is preliminary or provisional and is subject to revision. It is being provided to meet the need for timely best science. The information has not received final approval by the U.S. Geological Survey (USGS) and is provided on the condition that neither the USGS nor the U.S. Government shall be held liable for any damages resulting from the authorized or unauthorized use of the information.